Guidebook to Organic Synthesis by
The subject of this book is a core constituent of undergraduate chemistry courses. developments, and emphasizes the basic principles of the subject which remain essentially unchanged. Two new chapters on selenium reagents and asymmetric synthesis have been added.
Handbook of Reagents for Organic Synthesis: reagents for organocatalysis by
Spurred by the desire to make chemistry a sustainable and "greener" technology, the field of organocatalysis has grown to become one of the most important areas in synthetic organic chemistry. Organic catalysts can often replace potentially toxic metal catalysts and allow reactions to proceed under mild reaction conditions, thereby saving energy costs and rendering chemical processes inherently safer. More importantly perhaps, organocatalysis offers a complementary reactivity in many instances leading to increased versatility. This Handbook describes 126 key reagents for organocatalytic reactions and will be especially useful for professionals in the area of sustainable chemistry, medicinal research, as well as synthetic organic chemists working in academia and the pharmaceutical industry. All the information compiled in this volume is also available in electronic format on Wiley Online Library. The 126 reagents represented here are but a small fraction of the ca. 5,000 reagents available in the electronic Encyclopedia of Reagents for Organic Synthesis (e-EROS). e-EROS offers various search interfaces to locate reagents of interest, including chemical structure, substructure and reactions search modes. e-EROS is updated regularly with new and updated entries.
Innovative Catalysis in Organic Synthesis: oxidation, hydrogenation, and C-X bond forming reactions by
C-H, C-O, C-C, and C-Heteroatom bond forming processes by using metal-ligand approaches for the synthesis of organic compounds of biological, pharmacological and organic nanotechnological utility are the key areas addressed in this book. Authored by a European team of leaders in the field, it brings together innovative approaches for a variety of catalysis reactions and processes frequently applied in organic synthesis into a handy reference work. It covers all major types of catalysis, including homogeneous, heterogeneous, and organocatalysis, as well as mechanistic and computational studies. Special attention is paid to the improvements in efficiency and sustainability of important catalytic processes, such as selective oxidations, hydrogenation, and cross-coupling reactions, and to their utilization in industry. The result is a valuable resource for advanced researchers in both academia and industry, as well as graduate students in organic chemistry aiming for chemo-, regio- or stereoselective synthesis of organic compounds by using novel catalytic systems.
Modern Organic Synthesis: an introduction by
This book bridges the gap between sophomore and advanced / graduate level organic chemistry courses, providing students with a necessary background to begin research in either an industry or academic environment. * Covers key concepts that include retrosynthesis, conformational analysis, and functional group transformations as well as presents the latest developments in organometallic chemistry and C-C bond formation * Uses a concise and easy-to-read style, with many illustrated examples * Updates material, examples, and references from the first edition * Adds coverage of organocatalysts and organometallic reagents
Organic Synthesis by
A reactions oriented course is a staple of most graduate organic programs, and synthesis is taught either as a part of that course or as a special topic. Ideally, the incoming student is an organic major, who has a good working knowledge of basic reactions, stereochemistry and conformational principles. In fact, however, many (often most) of the students in a first year graduate level organic course have deficiencies in their undergraduate work, are not organic majors and are not synthetically inclined. To save students much time catching up this text provides a reliable and readily available source for background material that will enable all graduate students to reach the same high level of proficiency in organic chemistry. Produced over many years with extensive feedback from students taking an organic chemistry course this book provides a reaction based approach. The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to 'disconnect' a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists. The book is intended for graduate and postgraduate students, scientific researchers in chemistry New publisher, new edition; extensively updated and corrected Over 950 new references with more than 6100 references in total Over 600 new reactions and figures replaced or updated Over 300 new homework problems from the current literature to provide nearly 800 problems to test reader understanding of the key principles
Organic Synthesis: the disconnection approach by
A workbook providing additional examples, problems, and solutions for use with Warren's Organic Synthesis: The Disconnection Approach. Exercises correspond to chapters in the main text. Problems of special ease or difficulty are labeled for optional use. Workbook includes a formula index of all target molecules contained in the text and workbook.
Solvent-Free Organic Synthesis by
Chemical Synthesis without the use of solvents has developed into a powerful methodology as it reduces the amount of toxic waste produced and therefore becomes less harmful to the environment.Koichi Tanaka discusses the latest developments in this field, giving emphasis on the technology used as well as the practical applications. The book handles both theory and application of this field Includes instruction on the new technologies being used Valuable information to process chemists in industry, as well as academics and students
Foundations of Organic Chemistry by
This book differs from other organic chemistry textbooks in that it is not focused purely on the needs of students studying premed, but rather for all students studying organic chemistry. It directs the reader to question present assumptions rather than to accept what is told, so the second chapter is largely devoted to spectroscopy (rather than finding it much later on as with most current organic chemistry textbooks). Additionally, after an introduction to spectroscopy, thermodynamics and kinetics, the presentation of structural information of compounds and organic families advances from hydrocarbons to alcohols to aldehydes and ketones and, finally, to carboxylic acids.
March's Advanced Organic Chemistry: reactions, mechanisms, and structure by
The new, revised and updated 7th edition of March's Advanced Organic Chemistry clearly explains the theories and examples of organic chemistry, providing the most comprehensive resource about organic chemistry available. Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The first five chapters deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Chapters 6 to 9 are concerned with general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation, and finally the relationship between structure and reactivity. The last 10 chapters cover the nature and the scope of organic reactions and their mechanisms. The 7th edition proves again it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Key features of the 7th edition: Every chapter has been updated with the most recent reaction information with references to both the primary and review literature New to the 7th edition: 5,500 references since the last edition, updates / rewrites of the retained sections, and an updated index in Appendix B Contains more than 1650 reactions and 20,000 valuable references to the primary literature Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds synthesized Guides the reader on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. Reviews of the previous edition: "...a favorite general organic chemistry text and an easy-to-use one-volume reference. We are confident that this book will remain a dominant reference and that it will reside on many chemists' personal bookshelves." -Journal of Medicinal Chemistry "Who can hope to be seriously accepted as a member of the organic chemistry community without being in possession of at least one edition of 'March'?" -Chemistry and Industry
Organic Chemistry by
A new style of textbook, needed because almost all current organic chemistry texts are written to a fixed American pattern. This text is different from these in a number of important ways: The approach is based on explanation rather than fact. The functional group approach (alkane, alkene,alkyne) has served American State College readers well but increasingly students and instructors are attracted more to an approach based on mechanism and reaction type. This approach aims at understanding rather than factual knowledge and, though slower at the start, eventually gives the studentpower to understand compounds and reactions never previously encountered. This is a big advantage in a science already too large for individuals to learn and which is annually expanding at an ever greater rate. The basics of the subject are explained carefully and thoroughly. How to draw moleculesrealistically and how to draw mechanisms to reveal the fundamental chemistry are both emphasised. Important points are revisited when they become relevant in later chapters. Examples are very important too. New examples are given each time a concept resurfaces, and examples from everyday life andmedicinal chemistry are frequently used. The authors want the readers to be excited by the universality of organic chemistry rather than be overwhelmed by facts. The design of the book has features to help comprehension. Structures are drawn in red, and black is used on them for emphasis. Othercolours are used flexibly to draw attention to atoms, molecules, orbitals, arrows or whatever the authors want to emphasise rather than being used in a rigid systematic way. There are four types of "box" used to separate material from the main text, ranging from extra important summaries todiversions which can be omitted at first reading. The early chemistry chapters feature carbonyl group reactions because addition to carbonyl groups is probably the easiest reaction to understand. Thereafter the chemistry develops in a logical sequence but chapters on spectroscopy, stereochemistryetc are interspersed among those dealing with chemical reactions. From time to time review chapters summarise what has been described in a particular area. A personal and honest approach is adopted. The authors write clearly and directly to the reader, sharing their enthusiasms, understandings anddoubts. If they believe an explanation is imperfect or controversial, they say so. They show that organic chemistry is developing rapidly, and that new ideas continually emerge to replace the old. The authors know from experience what conceptual difficulties often overwhelm students at an earlystage in their studies and they devote more space to these points, give more examples, and revisit them when they can be applied. The aim is to help the readers master these points for themselves rather than just learn them off by heart.
Organic Chemistry : an acid-base approach by
Based on the premise that many, if not most, reactions in organic chemistry can be explained by variations of fundamental acid-base concepts, Organic Chemistry: An Acid-Base Approach provides a framework for understanding the subject that goes beyond mere memorization. The individual steps in many important mechanisms rely on acid-base reactions, a
Organic Chemistry : an intermediate text by
Ideal for those who have previously studies organic chemistry but not in great depth and with little exposure to organic chemistry in a formal sense. This text aims to bridge the gap between introductory-level instruction and more advanced graduate-level texts, reviewing the basics as well as presenting the more advanced ideas that are currently of importance in organic chemistry. * Provides students with the organic chemistry background required to succeed in advanced courses. * Practice problems included at the end of each chapter.
Organic Chemistry: Structure, Mechanism, and Synthesis by
There are no shortcuts in organic chemistry. Understanding and mastery cannot be achieved without devoting adequate time and attention to the theories and concepts of the discipline. It is with this premise that Ouelletteand Rawn set out to comprehensively survey the field in "Organic Chemistry," with an emphasis on connecting the basic principles of organic chemistry to real world challenges that require analysis, not just recall. Organic chemistry is at the interface of physical and biological science, and this new text lays out the basic principles of organic chemistry in their relation to a host of other fields in both physical and biological sciences. Chemical bonding determines molecular structure, which in turn dictates physical, chemical, and biological properties from the smallest molecules to the largest. Molecular structure determines reaction mechanisms, from the smallest to the largest molecules. Reaction mechanisms determine strategies for organic synthesis, and these synthetic principles extend to every aspect of synthesis, from drug design to the methods cells employ to synthesize the molecules of which they are made. These relationships form a continuous narrative throughout the book, wherein principles logically evolve from one to the next, from the simplest to the most complex examples, with abundant connections between the text and real world applications. Contains extensive examples of biological relevanceIncludes an important chapter on organometallic chemistry not found in other standard referencesExtended, illustrated glossaryAppendices on thermodynamics, kinetics, and transition state theory"
Organic Chemistry Laboratory Techniques by
This resource was created by Lisa Nichols (chemistry faculty at Butte Community College in Northern California) as a result of an academic sabbatical leave in the Fall-2015 to Spring 2016 term. The target audience are undergraduate students in organic chemistry.
In this resource you will find theory and procedures on the main organic lab techniques (chromatography, crystallization, extraction, distillation) as well as general concepts on how to set up and heat apparatuses (see the Table of Contents tab for a more complete listing of topics).
All procedures are accompanied by step-by-step pictures, and graphics are heavily utilized throughout the resource.
Organic Chemistry Reactions by
Quick Reference for the core essentials of a subject and class that is challenging at best and that many students struggle with. In 6 laminated pages our experienced chemistry author and professor gathered key elements organized and designed to use along with your text and lectures, as a review before testing, or as a memory companion that keeps key answers always at your fingertips. As many students have said "a must have" study tool. Suggested uses: o Quick Reference - instead of digging into the textbook to find a core answer you need while studying, use the guide to reinforce quickly and repeatedly o Memory - refreshing your memory repeatedly is a foundation of studying, have the core answers handy so you can focus on understanding the concepts o Test Prep - no student should be cramming, but if you are, there is no better tool for that final review
Organic chemistry with a biological emphasis. Volume I by
The traditional approach to teaching Organic Chemistry, taken by most of the textbooks that are currently available, is to focus primarily on the reactions of laboratory synthesis, with much less discussion - in the central chapters, at least - of biological molecules and reactions. This is despite the fact that, in many classrooms, a majority of students are majoring in Biology or Health Sciences rather than in Chemistry, and are presumably taking the course in order to learn about the chemistry that takes place in living things.
In an effort to address this disconnect, I have developed a textbook for a two-semester, sophomore-level course in Organic Chemistry in which biological chemistry takes center stage. For the most part, the text covers the core concepts of organic structure, structure determination, and reactivity in the standard order. What is different is the context: biological chemistry is fully integrated into the explanation of central principles, and as much as possible the in-chapter and end-of-chapter problems are taken from the biochemical literature. Many laboratory synthesis reactions are also covered, generally in parallel with their biochemical counterparts - but it is intentionally the biological chemistry that comes first.
Organic Chemistry with a Biological Emphasis Volume II by
The traditional approach to teaching Organic Chemistry, taken by most of the textbooks that are currently available, is to focus primarily on the reactions of laboratory synthesis, with much less discussion - in the central chapters, at least - of biological molecules and reactions. This is despite the fact that, in many classrooms, a majority of students are majoring in Biology or Health Sciences rather than in Chemistry, and are presumably taking the course in order to learn about the chemistry that takes place in living things.
In an effort to address this disconnect, I have developed a textbook for a two-semester, sophomore-level course in Organic Chemistry in which biological chemistry takes center stage. For the most part, the text covers the core concepts of organic structure, structure determination, and reactivity in the standard order. What is different is the context: biological chemistry is fully integrated into the explanation of central principles, and as much as possible the in-chapter and end-of-chapter problems are taken from the biochemical literature. Many laboratory synthesis reactions are also covered, generally in parallel with their biochemical counterparts - but it is intentionally the biological chemistry that comes first.